Chronic neuropathic pain (CNP) is a common consequence of neurological conditions such as spinal cord injury (SCI), complex regional pain syndrome (CRPS), and phantom limb pain (PLP). These conditions are often associated with distorted body representation (BR) and altered sensory processing. Virtual reality (VR) offers immersive, multisensory experiences that can modulate attention, recalibrate BR, and potentially alleviate pain.This systematic review aims to synthesize evidence on the use of VR-based interventions for managing CNP in patients with neurological conditions. It explores how VR can influence pain perception through body remapping. Furthermore, this review seeks to identify gaps in current research, offering recommendations for future research directions and clinical applications.We performed a comprehensive literature search in PubMed, Web of Science, and Scopus for studies published between January 2014 and December 2024. We included original studies that examined VR interventions in patients with neurological conditions and CNP, assessing pain reduction, improvements in BR, or functional recovery. We excluded reviews, animal model studies, migraine-related studies, and those lacking a clear VR intervention or relevant clinical outcome data. The quality of the included studies was evaluated using the revised Cochrane Risk of Bias Tool for Randomized Trials and the Cochrane Risk of Bias in Nonrandomized Studies of Interventions tool. Given the heterogeneity in study design, VR protocols, and outcome measures …