Nowadays, recent advancements in ICT have sped up the development of new services for smart cities in different application domains. One of these is definitely healthcare. In this context, remote patient monitoring and rehabilitation activities can take place either in satellite hospital centres or directly in citizens’ homes. Specifically, using a combination of Cloud computing, Internet of Things (IoT) and big data analytics technologies, patients with motor disabilities can be remotely assisted avoiding stressful waiting times and overcoming geographical barriers. This paper focuses on the Tele-Rehabilitation as a Service (TRaaS) concept. Such a service generates healthcare big data coming from remote rehabilitation devices used by patients that need to be processed in the hospital Cloud. Specifically, after a feasibility analysis, by using a Lokomat dataset as sample, we measured and compared the performances of …