This article introduces Transformer Quantile Re-gression Neural Networks (TQRNNs), a novel data-driven solution for real-time machine failure prediction in manufacturing contexts. Our objective is to develop an advanced predictive maintenance model capable of accurately identifying machine system breakdowns. To do so, TQRNNs employ a two-step approach (i) a modified quantile regression neural network to segment anomaly outliers while maintaining low time complexity, and (ii) a concatenated transformer network aimed at facilitating accurate classification even within a large timeframe of up to one hour. We have implemented our proposed pipeline in a real-world beverage manufacturing industry setting. Our findings demonstrate the model’s effectiveness achieving an accuracy rate of 70.84% with a 1-hour lead time for predicting machine break-downs. Additionally, our analysis shows that using …